I am talking about the American President, of course. Did any First lady give birth while her husband was President? Who was the most recent?
Jacqueline Kennedy is the most recent. She gave birth to two of JFK's children during his presidency. The first was JFK Jr. in 1960, just a few weeks after his father's victory over Nixon in the election.
The second was another son, Patrick Kennedy, in August of 1963, but the child was born premature and died a few days later as a result of complications from this.