So I need to write an essay to argue if Shakespeare did or did not have syphilis. Some said he did due to his abnormal amount of referrence to venereal diseases and the fact that his later works are inferior to his earlier works because of brain damage caused by syphilis and mercury baths.
We're definitely happy to help when you're stuck on a specific question, but it sounds like you're asking us to outline your essay for you, and we don't do that here. A brief Google Scholar search turns up quite a few results, I'd recommend starting there.