I assume that the Jewish spouse was sent to concentration camps. I also assume that there were marriages between Jewish people and non-Jews. I also assume these couples had children. If I am wrong, let me know.
Were the non-Jewish spouses also sent to concentration camps?
Were the children treated as Jewish children?
The non-Jewish spouse would have been left alone. The children would have been considered Jewish if they had at least three Jewish grandparents (meaning that the non-Jewish spouse had one Jewish parent as well, but only two Jewish grandparents), or if they belonged to a Jewish congregation, or if they were married to a Jew. If they didn't fall into any of these categories, they were considered Mischlinge ("mixed [blood]").
In Germany and other Western European countries, Mischlinge were generally not deported but they were subject to a number of discriminatory measures in terms of marriage, jobs and education.
In Eastern Europe, these people were treated the same as "full-blooded" Jews.