Yes, extremely so late in the war. A spectacular example of this is the Battle of Stalingrad, which became increasingly untenable for the Germans. Hitler however, forbade retreat and the bulk of German forces were surrounded by the Soviets. Even then, Hitler refused to allow retreat or surrender and even promoted the general in charge at Stalingrad, Friedrich Paulus, to a marshal in the hopes that Paulus would refuse to allow himself to be the first German marshal to be captured.

As the war progressed and Germany's losses mounted, Hitler's ego and paranoia increasingly affected the military high command, with generals that disagreed with Hitler kicked out of the loop (Gerd Von Rundstedt, Heinz Guderian).