Well, I read the book, and some of the things in there are pretty shocking--when said in the TV show, I thought they'd made them up to make the 1950s sound really backwards, but in fact they were true.

For example, it was pretty frowned upon for women to get their tubes tied (even as some black women and some poor women of various races had their tubes tied against their will or without even telling them). At the hospital where Masters worked, few doctors would even do tubal ligations. But Masters' mentor there would do them--but only if the woman had already had at least 5 children and her husband gave his permission.

Masters genuinely did not know about the idea of faking orgasm. He couldn't wrap his head around it or understand what it was or why it would be done, when a prostitute told him about it. The prostitute, just as in the TV show, then recommended he get a female assistant to help him with these sorts of things.

He was shunned and got into trouble for his research, eventually having to leave the university and go independent.

Masters did coerce Johnson into becoming his mistress. Johnson understood that if she wanted to keep her job, she had to start having sex with Masters.