In /r/AskHistorians, we are very strict with the enforcement of our rules. Comments which do not meet those standards are removed. Commenting about how there are so many removed comments merely compounds the problem (more than half the top level comments are to that effect). Please do not comment in this thread unless you can provide a comprehensive response to the OP's question.
It should be noted that the procedure was quite common back then. (Actually it became even more common later, before it got shelved as a historically bad fad in medicine.)
Rosemary Kennedy was lobotomized in 1941. In 1949 the Nobel Prize in medicine got awarded for the development of the procedure. It quickly became medically mainstream for some conditions in the 1940s.
I find it difficult to blame the family of a victim (modern perspective) for what they were advised to do by medical professionals back in the day. Especially when it was done before most of the critcism began (late 40s, fifties - and even then it was still widely practiced). It actually was a rather early use of the procedure.
I think regret is most appropriate, not recrimination.
I do know that this does not diretly answer the question, I still think it should be pointed out (before being deleted, as it should be; sorry for the extra work, mods).
In Jacqueline Kennedy: Historic Conversations on Life with John F. Kennedy, Caroline Kennedy does go over it, though it's not in-depth, and it's more of a mere admittance that "Yes, it did happen...".
However, seeing her publicly present the book at the Fox Theatre, when the topic came up, she said quite a bit less about it than she did in the book, contrary to most other topics of the night, and she even seemed more apprehensive about discussing it than her father's assassination, or the Cuban Missile Crisis.
You might find these previous posts interesting: Did Joseph Kennedy lobotomize his daughter, Rosemary Kennedy, to preserve the reputation of his family? and Putting Rosemary Kennedy's Lobotomy & What Followed in Context.