The image is an etching of John Trumbull's famous painting of the Declaration of Independence. The Wiki article has a good who's who.

The man who you singled out was Benjamin Harrison V. He was the father of William Henry Harrison, killer of Tecumseh and our first President to die in office (also shortest term). His great-grandson was President Benjamin Harrison, probably best known for signing the Sherman Antitrust Act. Harrison V was known for his humor during the second continental congress.