Not for transportation purposes. Horses were not introduced to the Native Americans until the Spanish arrived and were not largely incorporated into any of their societies until 1680-1740. The animals used for transport were pack dogs that used sleds referred to as travois.

There is also an answer here (http://www.reddit.com/r/AskHistorians/comments/1aggse/the_native_americans_and_several_other_cultures/?sort=top), as this is among one of the frequently asked questions on this subreddit.

Some of the plains Indians (Pawnee, Omaha, Blackfoot, etc.) used wheel-like devices for entertainment and as a game in variants of hoop rolling, They would also send a hoop rolling along and use it for target pratice, either for spear or arrow. In some instances, such would become a game of skill, where prizes were awarded depending on the outcome. The Inuit also had a variant of this practice.

See:

• Indian Games By Andrew McFarland Davis; p44-56

• Sports and games of the ancients By Steve Craig; p181

• International Traditional Games Society. Indian Education for All - Traditional Games Unit (Revised 2013 ed.). Montana Office of Public Instruction.

• Travels in North America, Volume 2, By Sir Charles Augustus Murray; p19

However, the wheel was not adapted to transportation.