The Americas notably lack native large domesticated animals to the extent that Afro-Eurasia possesses. One available large species that humans did rely on as a food source was bison. Why didn't they domesticate bison the way others domesticated aurochs?
Pray allow me to refer you to the discussion in this earlier thread:
http://www.reddit.com/r/AskHistorians/comments/w9v9j/why_didnt_the_plains_indians_try_to_tame_the/