Was there backlash against these businesses? Are any of these businesses still operational today?
For one thing, the rice economy of South Carolina proved entirely unprofitable without slave labor and collapsed utterly.
As an aside, it should be noted that any business which relies on exploiting its work force to exist should not be called 'successful' by any measurement, because even if the owners/operators managed to accrue quite a large pile of money, they are in effect stealing the wages from their workers and calling it 'profit'...