What led to the Chinese isolationism during the Ming dynasty?

by getawaywithmurder

Also, what were the ramifications of the isolationism? I know about the Opium Wars, but how did this affect how the Chinese populace viewed Westerners?

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You might be interested in a previous answer on the topic:

Why did Ming China institute a policy of isolationism and was this the cause of China losing the technological and economic edge it had over other societies at the time (i.e. Europe)?