fyi, you'll find some previous responses in these threads

• Were the Habsburgs aware about the dangers of inbreeding?

• Did the Hapsburgs have any clue that their marriage traditions were weakening their lineage?

• Did European dynasties know that their inbreeding was causing progressively worse problems?

• Were historic Royal Families aware of the effects of inbreeding?

• Did people in medieval Europe ever link birth defects to inbreeding? If not, when was that link found?

if you have followup questions on locked posts, ask them here & include the user's username so they'll be autonotified