I'd like to know what other major ontological systems were offered to explain both chemistry and the practice of medicine from the Ancient world to the 17th century.
I am not sure if I can answer all of your questions adequately in one comment, or even a series of comments, but I recently read a book dealing with these topics.
The title is "The Upright Thinkers" by Leonard Mlodinow. I hope you found my response marginally helpful.