Great question! Fortunately, there are already several posts asking the same, and you may want to read through some of the answers:
https://www.reddit.com/r/AskHistorians/comments/3bqsd7/how_did_the_orthodox_church_respond_to_the/
https://www.reddit.com/r/AskHistorians/comments/1ym04m/to_what_extent_if_at_all_did_the_protestant/
Feel free to ask further questions!