EDIT: My apologies if this question is below a standard any historian may have for answering. I'm leaving it up to see who might actually answer, and how many more downvotes it can get.
I read that syphilis most likely was in the Americas prior to the Colombian era, and some of the Europeans returning home were who brought it to the Old World first. That's not terribly certain but I'm looking for similar anecdotes along with whichever few go back furthest in time. Some ancient cultures may not have had a taboo on sex like our modern day seems to have, so surely there were diseases that were around. HIV was only discovered/given a name in the end of the last century, so (subquestion here) have diseases in the past just popped up out of nowhere in cultures and caused any epidemics or hysteria?
Thank you in advance. I tried looking in this subreddit's post history and no one has seemed to ask this exact question. Just questions about STDs in Greco-Roman times.
I just realized this might be more appropriate at /r/history and not here with learned historians. My apologies. I'll leave it up just because, but also cross post it in /r/history.