hi, you may be interested in /u/sunagainstgold's answer last week to this related question

• I've often heard that the Middle East was "Arabized" over the course of history. Does this mean that there were other ethnic groups that were wiped out over the course of time?

You can look up haplogroup maps for mitochondrial DNA and Y-DNA, for maternal and paternal lineages, respectively. They are available on Wikipedia and a number of sites have specialized analysis of specific groups and regions. I've seen some for Anatolia though not the Middle East proper. Wikipedia has this table but it doesn't tell much - the major haplogroup columns there are tens of thousands of years old. You would want to look for more detailed haplogroup studies - tracing populations of known origins - and I'm not sure if one has been done for the Middle East (it seems like it should, but a cursory search isn't turning one up).

The general answer is that the shift is almost entirely cultural, however. This is true not just for the Middle East but nearly the entirety of the Old World and a fair portion of the New. Invasions have surprisingly little impact on the genetics of established populations.