More specifically politically. Did rivers have any impact politically on places like Mesopotamia or Egpyt? I am trying to think of ways but am hitting a brick wall, I even have my book with me and am trying to find some information but can't. Any way one of you can help?
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With that said, here are two things to get you jump-started while you are doing your research:
Go to an historical atlas - not an old one, but one drawn to show the layout of past eras in modern cartography. Look at your chosen era. Can you find any major cities that are not on rivers? The ones that aren't have sea ports. Water transport was the only way to move goods in bulk.
In the ancient world, city-states are the norm, even though they are in the same civilization. Unified kingdoms like Egypt are rarer (& often disunified into cities), and an empire like Persia a real super-power. Look at how they lie along rivers.
In Asia, you can see similar patterns. In pre-Columbian North America, rivers like the Missouri and Mississippi form the backbone of civilizations. Look into where and when these cultures formed.
The Penguin Atlas of the Ancient World gives you a start on the Mediterranean world. Also look for the "Cultural Atlas" series, on Greek World, Roman World, China &c.
Good luck.