How did Byzantium react to The Holy Roman Empire from it's creation till Byzantium was conquered by the Ottomans?

by darth_Marshmallow
Simplerockets64

You might enjoy this. https://www.reddit.com/r/AskHistorians/comments/219jdm/what_kind_of_relations_did_the_byzantine_empire

(I'm not a professional, but all I did was link a thread from the same subreddit, so...)