Yes. Eisenhower changed his stance on atomic weapons incredibly quickly after a quote that in the context of today makes him into a different beast from a different time.

Here is his quote on whether small atomic weapons would be used if war broke out in the Far East. Press conference March 16, 1954.

"Yes, of course they would be used. In any combat where these things can be used on strictly military targets and for strictly military purposes, I see no reason why they shouldn't be used just exactly as you would use a bullet or anything else."

then later:

"We are in the era of the thermonuclear bomb that can obliterate cities and can be delivered across continents. With such weapons, war has become, not just tragic, but preposterous.

Republican National Convention, August 23, 1956."

source: https://www.nps.gov/features/eise/jrranger/quotes2.htm

I am not sure if it just took a day or more, but reportetly his phone was ringing all day with questions about very concerned people who could not believe what Eisenhower said. (or more importantly: what it MEANT if not confronted with a counter reaction)

Also Eisenhower's quote can be also explained in the typical politican sense, that he just wanted to test the waters for another potential political instrument and found the risks "too hot".

So without getting politically in my post, you have to remember that all it takes is for politicans thinking that they can get away with something or that the emotion will die down to pass something that even the majority of people are actually against. It's all about mobilization.

Edit: Nagasaki und Hiroshima were claimed to be military targets, but you don't hear anyone use that as a defence, because it's just so obvious to us knowing the effects of nuclear weapons, that you almost never can just use it purely on military targets.