I have heard about mandragora and belladona extracts being used to dilate pupils for matters of beauty, but that might have been for Roman ladies. I wonder what kind of products and materials would they use, if some of it was dangerous and what kind of tools they used to apply it (for example I do know that some fine brushes are made from goat hair today, would something similar be avalaible?). The range is deliberately vague, but I was basically wondering about 12th - 14th century Europe.