Hi, not discouraging new/more/deeper info here, but fyi there have been some in-depth discussions on this topic. Check out the FAQ section Americas Before Columbus and Native American History | Disease in the Americas | Impact of indigenous diseases on the Europeans :
I am a native american living in the 1600s, someone in my village has just contracted small pox. What happens next? by /u/anthropology_nerd
When Europeans brought diseases to the new world, how come Europeans themselves didn't get sick from diseases specific to the new world? by /u/anthropology_nerd
Why weren't European settlers in North America decimated by disease like the native populations? by /u/400-Rabbits