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Something similar's been asked before (at least on the Nazi side). I don't think this fully answers your question, but /u/commiespaceinvader 's answer has some good points and some further sources.
You're definitely not discouraging discussion, these are actually the answers I was looking for! Many thanks. I'll be following up with some of the book titles listed in one of the answers as well.
Gynecological advances in the form of the speculum (used to give pap smears and other cervical exams) and the cure to vesico-vaginal fistula (both of which were developed by the same person). This condition happens when, during childbirth, a hole between the vaginal wall and the bladder/rectum forms, leaving excruciating pain and incontinence. The condition was endemic in the early 19th century, and still remains a problem in Africa and some regions of Asia. A southern doctor, J. Marion Sims, found a surgical method that permanently cured vesico-vaginal fistula - an advancement that has been incredible for women since. The way he discovered this surgical method, however, was not great for women: he operated, without anesthesia, on female slaves, some of whom underwent over twenty unanesthetized operations. Sims is a difficult figure to discuss now, because his contributions to gynecology are undeniable, but his completely unethical, arguably sadistic experiments are similarly obvious.