As far as accurate comparisons go--it's not really that possible. There is some work underway to trace the DNA of various vines to see where they might have diverged from each other, but even that only gets us so far and is limited to grapes, besides. Michel Bouvier has made some attempts to reconstruct the production of ancient wines, going off the claims of several vineyards combined with ancient modes and materials of production and storage; he chronicles this quest in Les saveurs du vin antique: Vins d'hier; vignernons d'aujourd'hui (2001).

The major difficulty in comparing off textual sources, of course, is that medieval writers wrote about wine very different from today's sommeliers. Aside from its transubstantiation in the Eucharist and related winepress/grapes/wine imagery, there are a couple major places wine appears in medieval sources. First, in pastoral discussions of the sin of gluttony. From these, it appears that wine could have a variety of alcohol contents and that, as today, individual medieval people had varying abilities to "hold their liquor." They were also well acquainted with hangovers and what looks from a modern standpoint like alcoholism. The suggested cures were predictably medieval and predictably worthless ("Think of Christ suffering in the Passion. Your withdrawal from alcohol is your baby version of that suffering.") One thing, just based on personal observation, is that the preachers I've read tend to stress wine as the drunkmaker, while profane/comedic literature focuses more on ale and beer. That's not a complete dichotomy, just a general trend. (Preachers don't love the ale-house/tavern, mind you.)

The other major body of literature where wine features is actually in medical treatises, since wine was a crucial component of so many cures. (Hot wine is noted in the Trotula as a cure for weird pre-menstrual and menstrual food cravings, a personal favorite of mine.)

Recommended reading here is unquestionably Azelina Jaboulet-Vercherre, The Physician, the Drinker, and the Drunk: Wine's Uses and Abuses in Late Medieval Philosophy, which is as much footnotes as text across Latin, French, Italian and English sources.