I know about Greek comedy making fun of the elites while said elites were present, so mostly wondering about it making fun of what you may call "the common folk", so ordinary citizens that are sitting right there.
This conceit is very common in Aristophanes. There's a joke in Birds about the actors going and having sex with the councillors' wives while they're all in the theatre, but possibly the most famous line is from Frogs:
DIONYSUS But tell me, did you see the parricides And perjured folk he mentioned?
XANTHIAS Didn't you?
DIONYSUS Poseidon, yes. Why look! I see them now.
It's generally accepted this is accompanied by Dionysus gesturing to the audience.