To some extent, yes. In historic preservation and art conservation, tobacco smoke residue is an issue - the smoke creates a brown film that sits on top of wall coverings, paintings, and other artifacts, and the particulates in the smoke can also start corrosion on metal surfaces. The effects of tobacco smoke are mitigated, however, by ventilation and air flow. The high ceilings in many rooms like those in The Crown help to disperse the particulates and prevent them from building up on individual pieces.

But on the whole, these monumental rooms did not see much tobacco usage. Smoking was not always the neutral pastime that it was in the mid-20th century. In the early Victorian era, men were expected to refrain from smoking in company - they would retire to the servants' hall at night or the stables in order to achieve the proper privacy - and, of course, women were not to smoke at all. During the second half of the 19th century, smoking rooms where a gentleman could smoke in comfort, or where multiple gentlemen would retire to enjoy cigars and port together, became more common in upper middle class and upper class homes and clubs. These smoking rooms are where you will find much more tobacco residue on the walls and artwork.