I'm thrilled you are interested in learning more about the history of the Americas. To start, you might like to check our Frequently Asked Questions for some quick information. I wrote a series on the various myths of conquest that crop up in the modern version of popular Native American history. By the way you phrased your question I think you would like the essays on death by disease alone and a pristine, uninhabited Eden. If you are looking for good books to dive into check our recommended book list. For newbies who want an engaging, general overview I recommend Mann's 1491: New Revelations of the Americas Before Columbus. Mann provided a great overview, and the bibliography of the book is a wonderful place to search for more reading on subjects you find interesting. Best of luck on this new reading adventure!