Well, sort of. They may have not been exactly what you think of today, but there were undoubtedly men who gave humorous speeches and people who went to these events to laugh.

One which comes to mind is Lucian, who lived in the second century AD. He was a prolific writer, famous for perhaps the first science fiction story, A True Story, about travelling to the moon and the sun and meeting weird aliens. My favourite is Alexander the False Prophet, about a real person. Alexander lived close to Sinope in Asia Minor and (according to Lucian) was a religious charlatan. He fooled the local rubes into thinking a puppet was a snake god. Much of what survives from Lucian is satire about society, not at all unlike modern comedians today.

Now Alexander is really hilarious, as you can imagine, but this was a written work. But Lucian also gave speeches which drew huge crowds. Many of these speeches were humorous in nature - basically people came to see him to laugh, just like people go to see stand-up comedians today.

Panegyrc on the Fly is one example which might have originally been given as a speech and was later written down. However, we aren't quite sure. There are suggestions that Lucian spoke extemporaneously, without prepared notes - kind of like a modern comedian heckling and joking with the audience.

It is possible, if not probable, that he was a versatile speaker and writer. Sometimes he joked extemporaneously like a comedian and sometimes he wrote serious literary pieces, like his praise of the Emperor Lucius Verus' mistress Panathea.

Lucian is a well-known example, but there was a flourishing industry of professional rhetoricians. They spoke to huge audiences on a variety of topics. Philosophy was a big one, as well as formal rhetorical exercises like Fronto's praise of dust. (It might seem odd to praise dust, but the trick was to make a speech which made dust interesting. A good speaker would use clever language, logical exercises and ingenious references to respected authorities like Homer and make dust praiseworthy.) There were also public speakers who used humour, similar to a stand-up comedian.