So I am not a full historian, BA in Japanese history, but this era is Japanese history is one of my favorites so I will do my best to help you with an answer anyway.

So Genzaburo was a child at the start of the Meiji Era, to make a lot of long history very short, the Meiji Era was was the end of heavily isolationist Japanese policy due to American pressure to open the country to trade and started in 1869 with the Meiji Restoration. This era of Japanese history is super interesting and includes a ton of interesting stories, but for now I will leave the history at this: the Japanese essentially saw the dangers of being colonized like China and other Asian nations and started Westernizing at a breakneck pace.

Back to Genzaburo though.

Genzaburo at 19 in 1886 had raised funds to study abroad in the US to study Christianity, which is what he wrote in his application for his travel documents. So anyway, this kid goes to America, lands in San Francisco and enrolls in San Francisco West Minster Prep School. During his time there he and 27 other Japanese christians would re-establish one of the Japanese Christian Missions in San Francisco's Mission district calling it in English the Japanese Young Men's Christian Association (in Japanese for those interested 日本人基督教青年會 (You can assume the 青年 at this point in history referred only to men, although you would be linguistically correct to say in literal translation to English it should have been Japanese Young People's Christian Association)). There was no direct connection between the YMCA and the JYMCA to my knowledge, but the naming convention basically ended up linking them together.

In 1888 he was chosen to serve at the Japanese American Presbyterian Church (where he would serve for 2 years) and while in that position he also joined Pacific Theological Seminary in San Francisco. In 1890 he would apply to and be accepted to the YMCA International Training school in Springfield, Massachusetts. His class was the first class to ever play Basketball. That's how he ended up in that picture.

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As to what happened after:

After graduation (1892) he returned to San Francisco where he would become an overseer of the JYMCA (which at this point had moved to Haight Street from the Mission District). In 1893 he would move to Wisconsin where enrolled at the University of Wisconsin at Madison. He would present his Doctoral Dissertation in 1901 and graduate from Madison. He married a Canadian Woman (1903) (whose name I can only find in Japanese so the English Spelling is unclear, but her name is listed as Mary C McClay?)and they had a daughter named Akemi (1906).

He worked in Mitsui Production Company and would become the general manager of their Hamburg operations in 1905. During WWI he was actually captured and held as a prisoner of war for a week because he stayed back in Hamburg to complete the liquidation of the branch. This experience left a schism in his relationship with Mary and she would take Akemi back to her native Canada leaving Genzaburo to return to Japan alone.

After returning to Japan, in 1918 he would leave Mitsui Production Company and remarry to a Japanese woman, whose name I cannot find in the interview records I am going through to answer this. In 1924 he would be elected to the board of directors of the Japanese National Public Broadcasting authority (Modern NHK).

Genzaburo would pass away in 1956 in Yoyogi Tokyo.

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Sources:
Kawamura Papers in the OAC

外務省外交資料館収蔵資料 (The Japanese Ministry of Foreign Affairs Records Library Documents)

YMCA Magazine Young Men's Era 1893, December 7th Edition

在米日本人長老教會歴史 (The History of the Japanese American Presbyterian Church) (1911 Edition)

As well as various interviews with Ishikawa and his family of the years.