Native populations in the Americas were devistated by contracting "new" diseases from the Old World via contact with European explorers. By my understanding, the European explorers were not afflicted to nearly the same degree, as they already had some level of immunity. Namely, their communities had been previously exposed to those same Old World diseases for several generations, thus selecting the population for people who were either immune or otherwise better equipped to survive bouts of that particular disease.
Is this initial presumption correct?
If not, what were the root causes of the differing disease outcomes between the native populations and the Europeans?
If yes, were the Europeans similarly afflicted with any "new" diseases from the New World after contact with the native populations? i.e., Was it a "two-way street"?
If it was reciprocal, what were the New World diseases that afflicted the Europeans, and why don't they feature as prominently in our kown history?
If it was not reciprocal, why?
Not to discourage further discussion, but you will find some excellent previous answers in our FAQ sections on disease exchange in the Americas from u/400-rabbits and u/anthropology_nerd.