We know Native Americans suffered greatly from diseases that were brought over from Europe, but were there cases of the opposite happening? If not, why not?

by Knight_of_the_Lepus

It just seems logical that there would've been diseases in the Americas that the Old World had never encountered, but I've never heard of that happening.

retarredroof

There is a section in our FAQs titled Impact of indigenous diseases on the Europeans. Look there for answers by u/anthropology_nerd and u/400_Rabbits. The bottom line is that the data suggest that there likely were New World diseases that befell European invaders.