With disease and death so common in Victorian England, I feel like this situation might've arisen quite a lot. So if a woman's parents and brothers passed away, who would gain control over her? Would she actually inherit if there were no close male relatives? Or could, say, a second-cousin-twice-removed swoop in and take 'control' over her life, so to speak?
Edit: That is to say, an unmarried woman, obviously.
I'm going to start off by quoting a previous answer of mine for an explanation of coverture:
Both England and, by extension, the English colonies and the ensuing United States practiced the principle of coverture, which did not mean that women and children were "lawful possessions" of their husbands/fathers. It meant that, because the Bible said that man and wife were one flesh, a woman's legal identity was subsumed into her husband's. Anything that had been or became hers was automatically his. She could not legally own property or earn money for her own use; she couldn't appear in court on her own behalf; if she sold something, her husband could compel the buyer to sell it back if he hadn't given his permission. Fathers automatically had full custody of their children even when the parents were married, and had the right to make all decisions relating to them.
As a result of coverture, serious money and property were passed down from men to men - if you wanted to control what happened to your money and make sure that it stayed in the family (by the patriarchal standard that "the family" means "people with your surname"), you wouldn't pass it down to a daughter, because whoever she married would get it. Instead, fathers gave their daughters money when they married, via a dowry, and the wealthy also made sure that the marriage contract included much of it being set aside for the daughter's maintenance once she was widowed. The vast majority of women only inherited furniture, clothing, and that sort of thing from their mothers and other female relatives.
So to sum up, women weren't property that traveled down the male line. In many ways, the situation of upper class women was like being property, but they were not literally entailed like a title and estate.
An unmarried and underage woman would need a guardian, who would likely be named in their recently-deceased parent's will. That guardian could be any adult above the age of majority, man or woman; an orphan could be sent to an aunt or an uncle, a godmother or godfather, a grandparent, a cousin, a brother or sister. She could still inherit the property itself if her father chose to leave it to her - if she had no brothers she was the obvious choice, if the property wasn't legally required to be handed down in the male line; women weren't barred from inheriting as a matter of course. A man couldn't turn up out of nowhere with proof that he was the only living male member of her family and take her inheritance away, or take her as his ward, unless there was some stipulation in the will for him to do so.