After taking control of Tenochtitlan, Spanish conquistadors faced stiff opposition as they tried to expand colonial control out if the Valley of Mexico. The Mixton and Chichimeca Wars, the centuries-long war in the Yucatán, and the prolonged conflicts in western Mexico cost the empire dearly.
What guerrilla or asymmetric warfare strategies/tactics were used to confront colonial expansion? How did those strategies differ region to region, or change over time?
Thanks in advance!
Since military history isn't my forte I can't give you a direct answer on this unfortunately. I have written on resistance to Spanish rule before, including urban uprisings in Mexico City, which might be interesting here:
https://www.reddit.com/r/AskHistorians/comments/8q2lfr/comment/e0toatl
There's also the edited volume "Indian Conquistadors" by Oudijk/Matthew that goes into this for most of the regions you mention, and even for Guatemala - though the focus is more on earlier, conquest period allies than later resistance.
Hope this helps a bit at least!