He was very much aware of Hus and the Hussites, and Bohemia was at his time mostly Hussite, until the Thirty Years War. During the Leipzig Disputation with Johann Eck in July 1519, Eck asked whether Luther agreed with Hus- this was a fairly standard line of attack, since Hus was widely known and recognised as having been a heretic. Though he denied being a Hussite himself, Luther said that many of Hus’s teachings were “plainly Christian and evangelical”, and he should no have been executed.
After the debate he read Hus’s works and received encouragement from Hussite leaders. Plenty of later Protestants (most famously in Foxe’s Book of Martyrs) would claim the Hussites as proto-Protestants.
Sources- These are both general sources but they should be sufficient for an answer on this sub I hope.
MacCulloch, Diarmaid, 2004, “Reformation: Europe’s House Divided”, Penguin Books
Eire, Carlos, 2016, “Reformations: The Early Modern World, 1450-1650”, Yale University Press.