I'm imagining some sort of "sea caravans" with many boats sailing from modern day Ecuador and sticking close to the coast until they arrived... where?, in modern day Michoacán?, Oaxaca?, somewhere farther south?
And once there... how did they communicate?, were there quechua translators in mexico?, or did nahuatl translators accompained the traders?. Also, I've heard that people in Mexico bought mostly copper from the southamericans but, what did the south americans buy?
There's always room for more discussion, but while we wait for further answers the FAQ has its own section on pre-colonial trade.
Of especial interest for you question:
Before European contact, how far did trade routes extend along the Pacific coast? by /u/Mictlantecuhtli, /u/retarredroof, and /u/RioAbajo
Indigenous peoples of Mesa Verde in Colorado and trade networks with the Maya? by /u/400-Rabbits and /u/RioAbajo
Hope this helps!