/u/sowser has previously offered critiques of Genovese's work and also written about Genovese's historiographical position briefly in this thread alongside /u/yodatsracist.

See also What role did slavery have in the industrial revolution, if any?

The answer is "yes, but with caveats." It is on the subreddit booklist, after all. But, like most history books, it is not the only book you should read on the topic.