This isn't for a school assignment or anything, so I have free range. I've done interviews with her before, but that was focused on the personal lives of her family. Neat stuff, but for round 2 I'd like to think of questions in a broader historical context.
She grew up in San Fransisco, the daughter of French and Danish immigrants who started a laundry. The family moved when she was 10 to Bel Air, and she stayed within a 10 mile radius the rest of her life. She went to college at UCLA, and I'm not sure what degree she graduated with but she mostly worked as a receptionist before marriage.
Blew my mind when I realized she remembered the Golden Gate Bridge being completed. Anything specific I should ask her?
Right now all I have on my list is "Do you remember freeways being built/how did that impact your life?" and "Do you remember voting for the first time? Did your mother ever talk about voting?" (Her mother voted when the 19th amendment was ratified)
If it were me, I think I'd ask her what seemed most important to her and the people she knew at various stages of her life (maybe read around to see if there are any historical/cultural moments that interest you). Could be political, big H history, but from her standpoint: what sorts of things were people worried about or excited about or angry at, etc. Or, you could go into more light-hearted issues: what was her music scene, or favorite kind of movie? What styles of music, what bands did she like; or, who were the heart-throbbingest leading men?
I don't know if you have any interest in the Genealogy of your family, but asking her for the names, occupations and places of birth/residence of as many relatives as she can remember will help you (or someone else) to track them down.
I've just gotten to typing up my grandfather's life memories that he handwrote before he passed. He included things like his favourite subjects, his first job, his holiday to the beach, the musical instrument he played, and even an embarrassing memory. Unfortunately, he iy made it up to his emigration from Denmark to South Africa in 1950 before he passed.
Also check if she has anything on paper. My gran kept all their wedding cards, even the receipt for her engagement ring. And so many letters!
I am starting a family project now, and am putting together my own list for everyone. Of course memories of historical events are important, don't underestimate the mundane things. What her earliest memory is, what her parents personalities were like, what her mom made for breakfast.