I realize I am seeing a lot of seemingly conflicting info on the general Mesoamerican view on gender and sexuality beyond sexual excess being bad.
Especially since the god of homosexuality was also the god of pleasure, would that therefore mean the mesoamericans did not condone these identities because they are associated with excess?
I don't have anything specific to add about Muxe, unfortunately, but you may be interested in my past comment about Aztec views on homosexuality/queerness.
You might find this previous answer of mine which includes a discussion of Nahua queer gender identities interesting, though I don't discuss the Muxes there.