Yes -- see, for instance, Feyrer (2009) and a related essay in VoxEU.

At the outbreak of war in 1967, Egypt closed the canal. Shipping fleets were surprised by the war and the closure, and some ships were trapped in the canal for years.

Until 1975, the canal remained impassable as a hostile border between Egypt and the Israeli-occupied Sinai Peninsula. During the intervening years, Egypt and Israel remained enemies, and there were ongoing armed conflicts, such as the War of Attrition of 1969-1970 and the Yom Kippur War of 1973, also known as the Ramadan War or October War. This latter war gets its name from its timing, beginning on the Jewish holy day of Yom Kippur, but also taking place during the Muslim holy month of Ramadan. This timing allowed the Egyptian forces to cross the canal while Israeli defenses were at their weakest, enabling them to destroy the Israeli fortifications on the canal's eastern bank.

It was not until negotiations subsequent to this latter war that the canal was reopened. Until this occurred, it was not clear to anyone when the canal would reopen, or even if it would be reopened at all in the foreseeable future. In addition to the historical and political importance of the larger conflict surrounding the closure of the canal, this unexpected change in trade created a "natural experiment" that allows economists such as Feyrer (cited above) to investigate the effects of trade.