There were indeed many!

There were probably quite a lot more than we think that simply fizzled out and were never recorded.

A very famous example is the Mutiny at Sucro. (While this happened during one of the bajillion Punic Wars, and thus before the Marian reforms, aka, when the Roman military became the way we often see it in popular culture, but it's still an example.) At Sucro, a fort in Spain in 206, a garrison mutinied. Their major complaint was about a lack of pay and supplies.

Historian Stefan G Chrissanthos has written a paper not only about Sucro, but four other mutinies that occured during the same time frame. You can find it here.

Another famous incident occured in 342 BCE, when a garrison in Campania mutinied, and marched on Rome itself. The senate even elected a dictator, Marcus Valerius Corvus, to combat the crisis. Corvus marched out with an army of his own to confront them, and the whole debacle was solved peacefully. There's some scholarly debate over the details, and even if the incident happened, or was invented by later Romans!^(citation 1)

In his book, Gladius: The World of the Roman Soldier, historian Guy De La Bedoyere devotes an entire chapter to mutiny.

There was another mutiny on the Rhine, (apparently a popular spot for mutiny-ing), in 187 CE/AD. A soldier named Maturnus deserted a garrison, and convinced some other soldiers to join him. Quote "Forming not so much a rebellion as acriminal gang of malcontents who proceeded to raid villages and farms. The robberies provided him with so much money that other criminals were attracted to join him on the promise of a share of the loot." (Bedoyere, p. 256-57) [2020]. Eventually, the Emperor Commodus, (yes that Commodus, of Gladiator fame), reprimanded the governors of the respective provinces Maturnus robbed. Maturnus ordered his force to split into smaller raiding parties, and they made their way into Southern Italy. Maturnus decided that the Empire's plunder wasn't enough, so he'd seize the Empire. He and some of his men enacted a plot to assassinate Commodus during a festival, but some of his men were against the idea, and turned him in. The incident went down in history as the "Bellum Desertorum", the War of the Deserters. ^(citation 2)

Lastly, and perhaps in the most bizarre incident, was the Caurausian Revolt. Caurausius was a soldier from modern Belgium who had risen through the ranks in service of joint Emperors Diocletian and Maximianus. Caurausius was put in command of a fleet ordered to combat piracy on the coasts of Spain and Gaul. However, Caurausius was accused of waiting until the pirates plundered the coast, then simply stealing the loot from the pirates for himself. He was incredibly popular with his men, so much so that when things turned sour and Maximianus ordered Caurausius assassinated, he took his men, fled to Britain on the Empire's edge, and declared himself Emperor of Britain, taking the mouthful of a name Marcus Aurelius Mausaeus Carausius, and portrayed himself as a restorer of the good ole' days of Roman culture in the area. (Bedoyere, p. 264-65) [2020].

Diocletian and Maximianus had such trouble rooting Carausius out of his holdings that they eventually gave up and recognized him as ruler of Britain. Eventually however, Carausius was murdered by his minister of finance in 293.(Encyclopedia Britannica,) [no date].

I highly reccomend Bedoyere's Gladius if you're interested in more tales of Roman legionary mutiny.

(all citations and sources linked in the comment).