Has there ever been wars where a nation or a bloodline of people have been completely wiped out by conflict? Physically, and culturally?

by mrslakes

I noticed in many wars or battles for that matter, that a nation is never completely out in terms of remaining a player in a conflict. For example, during the Napoleonic wars France was constantly beating Austria to the curb and even conquered Austria at a certain point. But the Austrian people still existed. Austria as a nation, and as a culture was still somewhat there regardless of how battle scarred the nation was. Hitler committed genocide on the jews,but that still doesn’t change the fact that the Jewish population still exists today.

EnclavedMicrostate

I presume there are more examples to list, but this older answer I wrote on the 'Zunghar Genocide' of 1757-8 covers one of them.