Did Alexander the Great ever try or suggested conquering Rome or was he never interested in the italian peninsula?
See these previous, similar questions and their answers:
https://www.reddit.com/r/AskHistorians/comments/4fh7mu/why_didnt_alexander_the_greats_conquests_go_north/
https://www.reddit.com/r/AskHistorians/comments/177b7r/to_what_extent_was_alexander_the_great_aware_of/
https://www.reddit.com/r/AskHistorians/comments/2z1p52/what_did_alexander_the_great_think_about_roman/