I know there were large debates in Judaism about whether gelatin made from pig bones were kosher or not due to the tremendous amount of processing it underwent to be turned into gelatin. Did similar debates occur with insulin?
From a pure Jewish law perspective insulin isn't really a question. Jewish dietary law prohibits eating pigs, but not other ways of benefitting from pigs^(1,2). This is unlike, say, forbidden mixtures of milk and meat, which are not only forbidden foods but are also forbidden to benefit from. Even if insulin were "eaten", people who need insulin are at serious risk of developing dangerous health conditions if they don't take it, and one is allowed to eat forbidden foods if one will otherwise be in danger^(3). This is without getting into the gelatin debate about whether heavily modified derivatives of non-kosher animals lose their status as being from the original animal--even if it were universally agreed that gelatin and similar animal-derived products are totally not kosher^(4), insulin would be fairly clearly permitted^(5).
As a historical question, though, one could ask whether this raised questions of Jewish law that were posed to Rabbis. The issue here is that unless something is truly earth-shattering, most questions are asked and answered orally. Because there's very little novel in the question of insulin, it's not the sort of question which would necessarily be put into writing. "Can I take this medication without while I will be in serious danger" is an important question, but not one that requires the sort of complex answer that requires being put into writing. There's already discussion in Jewish law from much earlier periods about medicinal forbidden foods, so insulin really breaks no new ground.
I am personally unaware of any written evidence of the question even being asked about insulin, and cannot find any in a cursory search. It probably was asked to Rabbis, but the answers not put in writing. I suspect it would have been asked is that Jews often have an aversion to pork products that goes beyond the technical limits of Jewish law^(6), and presumably the Rabbi would've answered without asking a question of a Rabbi of greater authority (which is what tends to generate documentation of halakhic questions).
So really insulin is not subject to being kosher or not. Presumably Jews asked questions of their Rabbis if they were aware of the origin of the insulin, but it did not generate significant written discussion in Jewish law, probably because it's a fairly open and shut case.